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Image Search Results
Journal: Journal of Cellular and Molecular Medicine
Article Title: Pancreatic cancer cell–derived exosomal microRNA‐27a promotes angiogenesis of human microvascular endothelial cells in pancreatic cancer via BTG2
doi: 10.1111/jcmm.14766
Figure Lengend Snippet: Inhibition of tumour growth and angiogenesis of PC in vivo are induced by miR‐27a silencing. A, Tumorigenesis of PANC‐1 cells following the injection of lentivirus with miR‐27a mimic and miR‐27a inhibitor. B and C, Tumour volume and weight after alteration of miR‐27a. D, The expression of miR‐27a in serum exosomes of nude mice after alteration of miR‐27a. E and F, Protein levels of BTG2 and VEGF in tumour tissues of nude mice after alteration of miR‐27a. G and H, MVD in tumour tissues of nude mice after alteration of miR‐27a (400×). * P < .05 vs nude mice injected with lentivirus with miR‐27a mimic‐NC or miR‐27a inhibitor‐NC. The above data are measurement data and described as mean ± standard deviation. The data of Panel B are analysed by repeated measurement ANOVA; data of other panels are analysed by one‐way analysis of variance. n = 12. The experiment was repeated 3 times independently. miR‐27a, microRNA‐27a; BTG2, B‐cell translocation gene 2; PC, pancreatic cancer; NC, negative control; MVD, microvessel density; VEGF, vascular endothelial growth factor
Article Snippet: All the
Techniques: Inhibition, In Vivo, Injection, Expressing, Standard Deviation, Translocation Assay, Negative Control